Think of Sister City Cruises as your waterway concierge. The soul of the company is taking guests on overnight cruises to historical seaports around the Lowcountry. A coastal area stretching from Charleston to Savannah, the Lowcountry is replete with virginal sea islands, intriguing waterways, and rare and exotic wildlife. Ports of call include Charleston, Georgetown, Beaufort, Hilton Head, and Savannah. We offer day cruises too. Book your dream cruise today.